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The meta-analysis indicates that a period of listening to Mozart can give an average reduction in epileptic seizures ranging from between 31% to 66%, but this varies from person to person and according to the music stimulus used. The original studies on the Mozart Effect used the sonata for 2 pianos, K448, and this has remained the music most used in studies. The K545 piano sonata has also been shown to have an effect.
Dr. Sesso said, "All cultures have music, so it obviously fulfills some psychological need. The mechanisms of the Mozart Effect are poorly understood. Obviously other music may have similar effects, but it may be that Mozart's sonatas have distinctive rhythmic structures which are particularly suited to working on epilepsy. This may involve several brain systems, but this would need to be proven. This is a review of research, and not original research. One thing it shows is that we need more consistent studies into the effect of music on the mind"
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Dr. Vesta Steibliene, Lithuanian University of Health Sciences, and member of the ECNP Abstract and Poster Committee commented, "There is growing interest in non-invasive brain stimulation techniques in the treatment of neuropsychiatric disorders. This review revealed that Mozart music could be an effective non-invasive method of neurostimulation, reducing the frequency of epileptic seizures, even in hard to treat patients. However, in order to use this method in clinical settings, the exact mechanism of the Mozart music effect on the brain regions should be better understood".
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